Replit co-founder and CEO Amjad Masad discusses the company's 10-year journey from a browser IDE to an AI-native "vibe coding" platform, empowering non-technical domain experts to build and deploy real software, and what the future holds with parallel agents and a post-prompting world.
Julian Goldie, CEO of Goldie Agency, shares his journey from fearing AI's impact on his SEO business to leveraging it to "100X" his operations. He discusses the paradigm shift from traditional SEO to Generative Engine Optimization (GEO), where the goal is to train LLMs to recognize your brand's authority. Julian provides practical strategies for using AI to automate content creation, marketing, and customer service, highlighting how tools like Claude Opus, HeyGen, and Google AI Studio can outperform human efforts and enable solopreneurs to build highly profitable, scalable businesses.
A recap of key conversations from the No Priors podcast in 2025, featuring insights from leaders at OpenAI, Harvey, and the Center for AI Safety on topics ranging from reasoning models and spatial intelligence to the geopolitical risks of superintelligence and the human impact of AI in healthcare.
Elias Torres, co-founder of Drift and Agency, discusses the prevalent expectation mismatch in AI adoption, where businesses demand AI but reject it due to "imperfection anxiety." Drawing from his experiences scaling HubSpot and Drift, he explains why human-led customer experience is fundamentally unscalable and details how his new venture, Agency, is building autonomous, AI-first solutions to solve deep, back-end customer challenges. His goal is to "deprogram the entire business world" from inefficient, human-dependent processes.
OpenEvidence founder Daniel Nadler explains how his company solved the semantic search problem in medicine, achieving 40% adoption among US doctors in 18 months. He discusses the strategy of treating physicians as consumers, the future of medical education in the age of AI, and his unique philosophy on motivation and recruiting.
Daniel Nadler, founder of OpenEvidence, discusses the platform's rapid adoption by 40% of US physicians. He explains how OpenEvidence solves the semantic search problem in high-stakes clinical decision-making, its growth strategy of treating doctors as consumers, and how AI will reshape medical education and the role of the physician.