Andrej Karpathy discusses the shift from 'vibe coding' to 'agentic engineering,' explaining why LLMs should be treated as 'ghosts'—jagged, statistical entities—rather than animals. He delves into the Software 3.0 paradigm, the limits of verifiability, and why human understanding remains the ultimate bottleneck in an age of outsourced thinking.
Cat Wu, Head of Product at Anthropic, discusses the radical shift in product development velocity, where shipping cadences have moved from months to days. She details the emerging skills required for AI PMs, emphasizing product taste, rapid iteration, and the importance of building for current, not future, model capabilities. Wu also explores Anthropic's unique mission-driven culture and provides practical advice for leveraging tools like Claude Code and Cowork to automate work and thrive in the AI era.
Will Falcon, CEO of Lightning AI, discusses the company's merger with Voltage Park to create a full-stack AI neo-cloud. He delves into the capabilities of Lightning AI Studio, a comprehensive platform for AI development, and recounts the origin story of PyTorch Lightning, from a personal research tool to a world-leading open-source framework.
Robin Bordoli of Weights & Biases explores AI's exponential growth, from past achievements to the current agentic landscape. He discusses the rise of reinforcement learning, the challenge of productionizing reliable agents, and highlights how foundational issues in AI development persist even as model capabilities soar.
a16z's Anish Acharya and Kevin Rose discuss how AI is fueling a renaissance in consumer technology. They explore the rise of emotional interfaces and AI companions, the importance of backing 'weird and working' founders, and how the modern AI development stack empowers solo creators to build, prototype, and launch products with unprecedented speed and craftsmanship.
Distinguished Engineer Chris Hay demonstrates how to run and program Large Language Models (LLMs) locally in just two lines of Python code. The tutorial covers setting up a local environment with Ollama and UV, using a custom library for simplified interaction, and explores advanced topics like asynchronous streaming, persona customization with system prompts, and managing multi-turn conversations.