Ciro Greco, CEO of Bauplan, outlines a new paradigm for data engineering that applies software engineering principles like version control, transactionality, and a code-first approach to build a programmable lakehouse designed for AI-driven automation and enhanced developer productivity.
Sajith Wickramasekara, CEO of Benchling, discusses the broken economics of drug development, where high costs and failure rates stifle innovation. He explains how the biotech industry is facing a 'dot com' bust and new competition from China, and argues that AI agents and simulation can provide the solution by making science less artisanal and helping scientists create better molecules through faster, cheaper experiments.
Emir Karabeg, co-founder of Sim, shares the journey of building a visual, end-to-end platform for AI agents. He discusses their pivot from a failed idea, their explosive open-source growth strategy, the philosophy of building an AI-native workflow tool, and the operational culture that took them from a YC batch to 60,000 developers.
Adam D’Angelo (Quora/Poe) and Amjad Masad (Replit) debate the future of AI. They clash on whether LLMs are hitting limits, the timeline to AGI, and the societal impact of automating entry-level jobs while expert roles remain, potentially creating a "missing middle" in the workforce.
Giga co-founders Varun and Esha discuss their product-first approach to enterprise AI, detailing their innovative 'AI Forward-Deployed Engineer' model that enables rapid, scalable customer support automation. They break down how they solve complex, multi-party use cases for clients like DoorDash and share their vision for expanding beyond support to become a comprehensive ops automation platform.
Snowflake CEO Sridhar Ramaswamy discusses the company's rapid transformation into an AI-first data platform. He introduces Snowflake Intelligence, an agentic system for enterprise data, and explores the strategic pivot, the ROI of AI for businesses, and the evolving roles of data platforms, partnerships, and search in the age of AI.