Llms in science

AI agents for therapeutic reasoning across biological contexts

AI agents for therapeutic reasoning across biological contexts

Medea is an AI agent for therapeutic reasoning designed to overcome limitations of existing AI in preserving biological context, verifying computational steps, and reconciling conflicting evidence. It employs a modular architecture with robust verification mechanisms for research planning, analysis, literature reasoning, and multi-round discussion, demonstrating superior performance in cell type-specific target nomination, synthetic lethality prediction, and immunotherapy response prediction across various biological contexts and data types.

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease

Priscilla Chan and Mark Zuckerberg of the Chan Zuckerberg Initiative (CZI) discuss their strategy to accelerate scientific discovery through the Biohub, an operating philanthropy at the intersection of frontier AI and biology. They detail the development of foundational tools like the Cell Atlas, a 'periodic table for biology,' and their new focus on building virtual cell models to allow scientists to test high-risk hypotheses in silico, ultimately aiming to cure, prevent, and manage all diseases.