Graph transformers

PhylaFlow: Hybrid flow matching in phylogenetic tree space

PhylaFlow: Hybrid flow matching in phylogenetic tree space

PhylaFlow is a hybrid flow-matching framework that navigates Billera–Holmes–Vogtmann (BHV) tree space to accelerate Bayesian phylogenetic inference. By learning geodesic paths from random trees to posterior samples, PhylaFlow efficiently initializes MCMC chains, drastically reducing the "burn-in" time. A PhylaFlow-MCMC variant, which guides MrBayes move acceptance, significantly outperforms traditional methods and even existing machine learning baselines for posterior sampling, achieving better results within the same computational budget. The work also explores conditioning on sequence embeddings, aiming for a future phylogenetics foundation model capable of zero-shot inference.

Graph Neural Networks Explained: A Clear Guide to GNN Basics & Models

Graph Neural Networks Explained: A Clear Guide to GNN Basics & Models

An introduction to Graph Neural Networks (GNNs), covering fundamental concepts like nodes, edges, and embeddings. This post delves into the core message-passing mechanism and provides a detailed overview of key architectures including GCN, GraphSAGE, GAT, GIN, and Graph Transformers, explaining their unique approaches and mathematical formulations.