Plenary Talk 3: Challenges and Research Opportunities for Global Hyperscale Services

This talk provides a comprehensive overview of cellular aging, brain function, and the mechanisms of cognitive decline, particularly focusing on Alzheimer's disease. It delves into the role of various cell types, neural communication, and methods for assessing cognition. The speaker highlights research challenges, the limitations of current pharmacological interventions, and the critical importance of non-pharmacological lifestyle interventions. A significant portion of the discussion is dedicated to the Centre for Brain Research's (CBR) multi-disciplinary efforts in India, including large-scale cohort studies, multimodal data collection, and the development of AI-driven tools and a localized foundation model for the Indian brain to address neurodegeneration.