Aug 19, 2026

How to build an AI-Native Health Company — Dan Feng, Maven Clinic

Dan Feng outlines Maven Clinic's transformation into an AI-native company, driven by the realization that "building is cheap and arguing is expensive" in the AI era. This shift has reshaped planning to short, iterative sprints, revolutionized software development with AI coding tools, forced adaptive changes in code review processes, and necessitated a nuanced, multi-layered approach to ensuring reliability in generative AI systems.

Jul 25, 2026

What Actually Makes A Startup Durable

YC partners discuss how founders should navigate the AI era, emphasizing the rapid decrease in AI costs, the evolving definition of a 'hard problem' for startups, the critical importance of human connection and co-founders, and practical advice on building AI-native loops, pivoting, and achieving distribution in a world where software is easy to build.

May 20, 2026

The ERP for the AI Revolution is here

John Glasgow, founder of AI-native ERP Campfire, discusses his journey from a Google Sheets MVP to displacing NetSuite. He covers the importance of founder-led sales to $1M ARR, using a narrow feature set as a wedge into the market, and how the rise of AI flipped the script on what constitutes a "safe" enterprise software choice.

Apr 24, 2026

How To Build A Company With AI From The Ground Up

Y Combinator Partner Diana Hu explains how to build an AI-native company where AI is the core operating system, not just a tool. She covers how to make a company queryable, the impact on team structures, and why startups have a massive edge in this new paradigm.

Dec 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

Experts from a16z outline three transformative ideas for 2026. Ryan McEntush discusses the rise of the 'electro-industrial stack' and the critical need for the U.S. to build a supportive industrial ecosystem. Angela Strange explains why financial services are at a tipping point, with AI-native platforms set to replace legacy systems, unify data, and create 10x winners. Sarah Wang predicts the emergence of a 'dynamic agent layer' that will overtake traditional systems of record by collapsing the gap between user intent and execution.

Dec 26, 2025

How AI Will Reshape The Economy In 2026 (a16z Big Ideas)

Experts from a16z forecast three major AI-driven shifts for 2026. Ryan McEntush discusses the rise of the 'electro-industrial stack' and the need for a U.S. ecosystem to power modern industry. Angela Strange explains how financial services are at a tipping point, with AI-native platforms unifying data to unlock massive efficiency gains. Sarah Wang predicts that a 'dynamic agent layer' will overtake traditional systems of record, fundamentally changing enterprise software by directly translating user intent into action.