Apr 02, 2026

Moonlake: Multimodal, Interactive, and Efficient World Models — with Fan-yun Sun and Chris Manning

Moonlake AI presents a distinctive approach to world modeling, prioritizing interactive, action-conditioned environments built on symbolic representations and game engines over purely pixel-based generative models. This method focuses on causal reasoning, long-term consistency, and programmable rendering (via their 'Reverie' diffusion model) to create dynamic, multiplayer worlds, positioning itself as a platform for training embodied AI and revolutionizing game development.

Apr 02, 2026

How Bots, Deepfakes and AI Agents Are Forcing a New Internet Identity Layer | Alex Blania on a16z

Alex Blania, cofounder and CEO of Tools for Humanity (Worldcoin), details the critical challenge of proving human uniqueness in the AI era. He explains Worldcoin's iris biometric approach, its sophisticated privacy architecture using Multi-Party Computation and Zero-Knowledge Proofs, and the pervasive impact of AI agents and deepfakes on social media, dating, gaming, and government. Blania also outlines Worldcoin's strategy to scale this proof-of-human network globally, particularly in the US.

Apr 02, 2026

Learning API Styles • Lukasz Dynowski & Sam Newman • GOTO 2026

This GOTO Book Club episode features an in-depth conversation between Sam Newman and Lukasz Dynowski, co-author of "Learning API Styles," exploring the foundational network layer of APIs, various API styles, critical trade-off decisions, and future trends like WebTransport and gRPC. The discussion emphasizes treating APIs as products, understanding consumer context, and the eight key characteristics of a well-designed API, complemented by a cautionary tale on database access.

Apr 01, 2026

Large-scale agentic quant research with Weights & Biases

Explore how Weights & Biases (W&B) enhances reliability, reproducibility, and explainability in large-scale, agent-driven quantitative research. This video demonstrates two core applications: debugging multi-agent alpha research pipelines with W&B Weave to identify root causes and iterate on forecasts, and automating strategy optimization using W&B Models to tune agent weights and gain insights from performance convergence and parallel coordinate plots.

Apr 01, 2026

"We're Not Writing Code by Hand Anymore. That's Over." | Owen Jennings & David Haber - The a16z Show

Owen Jennings, Executive Officer at Block, details the company's radical restructuring (40% workforce reduction) driven by AI's impact on productivity. He explains how Block is now operating with smaller squads, leveraging internal AI tools like Goose and Builder Bot, and shipping AI-native products like Money Bot and Manager Bot to deliver personalized, generative UIs for millions of users, emphasizing a future where unique understanding forms the ultimate business moat.

Apr 01, 2026

The Moonshot Podcast S2, Episode 2: Coding The Natural World

This episode of The Moonshot Podcast delves into the future of biological engineering, showcasing how AI and computational biology are transforming our interaction with living systems. Host Astro Teller first speaks with Brad Zamft of Heritable Agriculture about programming plants for increased yield, pest resistance, and drought resilience. Next, Relly Brandman from project A-Life explains how they're using AI to create a "virtual cell," shifting biomanufacturing from slow trial-and-error to a predictable engineering discipline for producing diverse materials like medicines, fuels, and textiles.