Tokenless

Transformer models

From Tokens to Cells: Foundation Models for Single-Cell Biology - Akram Baharlouei, Altos Labs

From Tokens to Cells: Foundation Models for Single-Cell Biology - Akram Baharlouei, Altos Labs

Akram Baharlouei from Altos Labs discusses the engineering hurdles in developing foundation models for single-cell biology. The talk covers the importance of single-cell analysis for cellular rejuvenation and drug discovery, the complexities and challenges of single-cell data (particularly RNA-seq), and a comparative analysis of current foundation model approaches, highlighting the limitations of transformer-based models and the potential of flow matching techniques like PrimeFlow.

AlphaGenome author roundtable

AlphaGenome author roundtable

A summary of the Google DeepMind team's discussion on AlphaGenome, their unified DNA sequence-to-function model. It covers the scientific motivation, the engineering breakthroughs in processing long DNA sequences at high resolution, the addition of complex biological modalities like splicing and contact maps, and the future direction of the research.

Arvind Jain on building Glean and the future of enterprise AI

Arvind Jain on building Glean and the future of enterprise AI

Arvind Jain, CEO of Glean, details the company's journey from a pre-LLM enterprise search innovator to a leading AI agent platform. He covers their hybrid model strategy, the critical role of permission-aware RAG for security, and how AI agents are creating 'evergreen' documentation and reshaping enterprise workflows.