AI agents for therapeutic reasoning across biological contexts

Medea is an AI agent for therapeutic reasoning designed to overcome limitations of existing AI in preserving biological context, verifying computational steps, and reconciling conflicting evidence. It employs a modular architecture with robust verification mechanisms for research planning, analysis, literature reasoning, and multi-round discussion, demonstrating superior performance in cell type-specific target nomination, synthetic lethality prediction, and immunotherapy response prediction across various biological contexts and data types.