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Too much lock-in for too little gain: agent frameworks are a dead-end // Valliappa Lakshmanan

Too much lock-in for too little gain: agent frameworks are a dead-end // Valliappa Lakshmanan

Lak Lakshmanan presents a robust architecture for building production-quality, framework-agnostic agentic systems. He advocates for using simple, composable GenAI patterns, off-the-shelf tools for governance, and a strong emphasis on a human-in-the-loop design to create continuously learning systems that avoid vendor lock-in.

How Scale AI is Pioneering the Future of Work

How Scale AI is Pioneering the Future of Work

Ben Scharfstein from Scale AI and a16z's Joe Schmidt discuss the nuances of enterprise AI adoption, contrasting vertical AI products with custom solutions. They delve into the 'forward-deployed engineering' model as a strategy to build durable moats by solving complex, specific enterprise problems, effectively 'trading margin for moat' in the new AI paradigm.

Building the Universal AI Automation Layer ft n8n CEO Jan Oberhauser

Building the Universal AI Automation Layer ft n8n CEO Jan Oberhauser

Jan Oberhauser, founder of n8n, discusses the company's strategic pivot from a workflow tool to an AI automation platform. He explains how focusing on community, adopting a "connect everything to anything" philosophy, and enabling the creation of complex AI agents led to a 4x revenue increase in just eight months.

Sub-Population Identification of Multi-morbidity in Sub-Saharan African Populations

Sub-Population Identification of Multi-morbidity in Sub-Saharan African Populations

A discussion on refining patient questions for a study on diabetes, highlighting the contrast between simplified questions for scalable data collection and the complex, nuanced queries from long-term patients. The team explores how to test their AI-driven storytelling system with these specific, real-world scenarios to generate more grounded and relevant health narratives.

Advanced Context Engineering for Agents

Advanced Context Engineering for Agents

Dexter Horthy of Human Layer explains why naive AI coding agents fail in complex software projects and introduces 'Advanced Context Engineering.' He details a spec-first, three-phase workflow (Research, Plan, Implement) designed to manage context intentionally, keeping utilization below 40% to maximize model performance. This approach uses subagents and frequent compaction to turn AI from a prototyping tool into a production-ready system for large, brownfield codebases.

Conext Engineering for Engineers

Conext Engineering for Engineers

Jeff Huber of Chroma argues that building reliable AI systems hinges on 'Context Engineering'—the deliberate curation of information within the context window. He challenges the efficacy of long-context models, presenting a 'Gather and Glean' framework to maximize recall and precision, and discusses specific challenges and techniques for AI agents, such as intelligent compaction.