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Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub

Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub

A panel with Google DeepMind's Pushmeet Kohli and Biohub's Sal Candido, moderated by Brandon Anderson, examines how AI should be built for biology. Topics include scaling laws and data quality, the bitter lesson applied to data, AlphaFold's handcrafted design and its limits, protein dynamics, cryo-EM as a richer data source, trust and calibration versus interpretability, and why curing disease requires 10x breakthroughs.

The Future of AI Molecular Discovery

The Future of AI Molecular Discovery

Professor Ellen Zhong discusses the shift from viewing proteins as static objects to dynamic molecular machines. She explores how cryo-electron microscopy (cryo-EM) combined with machine learning creates complex inverse problems to reveal protein motion, moving beyond the "solved" problem of static structure prediction and toward a future of AI-driven scientific discovery.