Derya Unutmaz, an immunologist, shares how AI, particularly Codex, is transforming biological research, from building custom cell analysis tools and T-cell simulators to envisioning a future of digital twins and personalized medicine, highlighting a coming "Science 2.0" paradigm.
Dexter Horthy of HumanLayer critiques the initial Research-Plan-Implement (RPI) framework for AI coding agents, revealing its tendency to encourage 'outsourcing thinking'. He introduces CRISPR, a new structured methodology that emphasizes smaller, focused prompts, human-agent alignment through artifacts like Design Discussions, and engineer ownership to combat 'slop' and improve code quality in complex projects.