Head of OpenAI for Science Kevin Weil and research scientist Alex Lupsasca discuss how frontier models like GPT-5 are beginning to accelerate scientific discovery. They cover real-world examples in physics, the evolving nature of human-AI collaboration in research, and the future trajectory of science in a new, AI-powered era.
Sajith Wickramasekara, CEO of Benchling, discusses the broken economics of drug development, where high costs and failure rates stifle innovation. He explains how the biotech industry is facing a 'dot com' bust and new competition from China, and argues that AI agents and simulation can provide the solution by making science less artisanal and helping scientists create better molecules through faster, cheaper experiments.
Dr. Jay Bhattacharya, Director of the NIH, discusses his vision for reforming the institution by adopting a Silicon Valley-style portfolio approach to funding, tackling the replication crisis, supporting early-career scientists, and leveraging AI to accelerate biomedical research while rebuilding public trust in science.