Entrepreneurship

No Priors Ep. 138 | The Best of 2025 (So Far) with Sarah Guo and Elad Gil

No Priors Ep. 138 | The Best of 2025 (So Far) with Sarah Guo and Elad Gil

A recap of key conversations from the No Priors podcast in 2025, featuring insights from leaders at OpenAI, Harvey, and the Center for AI Safety on topics ranging from reasoning models and spatial intelligence to the geopolitical risks of superintelligence and the human impact of AI in healthcare.

Why Businesses Are Rejecting the AI They’ve Asked For ft Agency CEO Elias Torres

Why Businesses Are Rejecting the AI They’ve Asked For ft Agency CEO Elias Torres

Elias Torres, co-founder of Drift and Agency, discusses the prevalent expectation mismatch in AI adoption, where businesses demand AI but reject it due to "imperfection anxiety." Drawing from his experiences scaling HubSpot and Drift, he explains why human-led customer experience is fundamentally unscalable and details how his new venture, Agency, is building autonomous, AI-first solutions to solve deep, back-end customer challenges. His goal is to "deprogram the entire business world" from inefficient, human-dependent processes.

No Priors Ep. 130 | With OpenEvidence Founder Daniel Nadler

No Priors Ep. 130 | With OpenEvidence Founder Daniel Nadler

OpenEvidence founder Daniel Nadler explains how his company solved the semantic search problem in medicine, achieving 40% adoption among US doctors in 18 months. He discusses the strategy of treating physicians as consumers, the future of medical education in the age of AI, and his unique philosophy on motivation and recruiting.

No Priors Ep. 130 | With OpenEvidence Founder Daniel Nadler

No Priors Ep. 130 | With OpenEvidence Founder Daniel Nadler

Daniel Nadler, founder of OpenEvidence, discusses the platform's rapid adoption by 40% of US physicians. He explains how OpenEvidence solves the semantic search problem in high-stakes clinical decision-making, its growth strategy of treating doctors as consumers, and how AI will reshape medical education and the role of the physician.