Jun 04, 2026

How a reasoning model cracked an 80-year-old math problem — the OpenAI Podcast Ep. 20

OpenAI's reasoning researchers discuss how a general-purpose AI model disproved an 80-year-old conjecture from mathematician Paul Erdős. They detail the journey from initial IMO/IOI breakthroughs to the verification of the proof, highlighting the model's creative application of advanced number theory. The episode explores the profound implications for the future of mathematics, AI-human collaboration, and the broader scientific landscape, offering advice for researchers seeking to leverage AI for groundbreaking discoveries.

Mar 27, 2026

AI agent adoption: From scientists to CFOs

This episode explores the transformative impact of AI through three key discussions: a homeowner using ChatGPT to sell his house, a study on AI adoption in scientific research, and Adobe's CFO building an internal AI lab. The experts deliberate on AI's role in democratizing expertise, the future of professional roles, the challenges and biases in measuring AI's scientific impact, and the critical factors for successful enterprise AI adoption, including process and cultural shifts, and identifying the hottest areas for implementation.

Nov 20, 2025

How AI Is Accelerating Scientific Discovery Today and What's Ahead — the OpenAI Podcast Ep. 10

Head of OpenAI for Science Kevin Weil and research scientist Alex Lupsasca discuss how frontier models like GPT-5 are beginning to accelerate scientific discovery. They cover real-world examples in physics, the evolving nature of human-AI collaboration in research, and the future trajectory of science in a new, AI-powered era.