Mar 11, 2026

Why AI Engineers Need to Understand GPU Hardware (with Chris Fregly)

Chris Fregly, author of 'AI Systems Performance Engineering', explains that true performance gains in AI come not from raw compute but from a deep, holistic understanding of the entire hardware and software stack. He emphasizes that memory bandwidth is the most critical GPU metric and introduces the concept of 'mechanical sympathy'—the co-design of hardware, software, and algorithms—as the key to unlocking efficiency and overcoming modern bottlenecks.

Mar 10, 2026

Build Hour: API & Codex

A deep dive into building agent-powered engineering workflows with Codex and OpenAI APIs, covering the shift from pair programming to agentic delegation, the principles of 'Harness Engineering' to make agents reliable, and practical examples from OpenAI and Basis.

Mar 10, 2026

10 years of AlphaGo: The turning point for AI | Thore Graepel & Pushmeet Kohli

Ten years after the historic match between AlphaGo and Lee Sedol, Google DeepMind's Thore Graepel and Pushmeet Kohli reflect on its legacy. They discuss how AlphaGo's blend of deep learning and tree search conquered the game of Go, the significance of creative breakthroughs like 'Move 37', and how these foundational concepts evolved into systems like AlphaZero, which learns without human data. The conversation bridges the gap from game-playing to solving scientific grand challenges, detailing how the same principles are now used in tools like AlphaTensor to discover novel, more efficient algorithms for fundamental problems like matrix multiplication.

Mar 10, 2026

The Top 100 Consumer AI Apps | The a16z Show

Anish Acharya and Olivia Moore from a16z discuss the 6th edition of their "Top 100 Gen AI Consumer Apps" report. They analyze the diverging strategies of ChatGPT, Claude, and Gemini; explore global adoption trends and cultural attitudes towards AI; and delve into the rise of agents, the importance of memory, and the future of creative tools and voice interfaces.

Mar 10, 2026

Physics Gets a Vote: Nominal Cofounders on Hardware Development in an AI World

Nominal's co-founders discuss the new age of reindustrialization and the critical need for a modern data infrastructure in hardware engineering. They explain how their platform acts as a 'GitHub for hardware data,' providing a system of record for testing that bridges the gap between simulation and reality, and serves as the essential verification layer for the future of 'Physical AI'.

Mar 09, 2026

How To Build The Future: Max Hodak

Max Hodak, co-founder of Neuralink and founder of Science, discusses the company's retinal implant that restores sight, the concept of the brain as a computer with a definable API, the surprising parallels between neural representations and latent spaces in AI, and the future of bio-hybrid interfaces.